Our research focuses on the structural dynamics and interactions of proteins. Particularly, we study the misfolding and aggregation of amyloid proteins that cause neurodegenerative disorders such as Alzheimer’s and Parkinson’s diseases. 

Our goals are to understand the disease process and to develop therapeutic strategies for manipulating protein aggregation, arresting protein aggregate toxicity, and detecting protein aggregates in vivo.

Our lab is involved in both fundamental and applied research, utilizing both experimental and computational tools, and is highly multi-disciplinary and collaborative, working at the interface of molecular biology, biophysics, and chemical engineering.